2025 Flu Seasonal. At least 24 million illnesses, 310,000 hospitalizations, and 13,000 deaths—including 57 children—linked to the flu had plagued the u.s. One indicator of flu activity is the percentage of doctor’s office visits driven.

Pediatric flu deaths hit a record 200 last year, and this season is shaping up to be worse, said matthew cook, president and ceo of children’s hospital association. The cdc estimates the flu has made at least 29 million people sick, caused 370,000 hospitalizations and resulted in 16,000 deaths since october 2024.